PM Jacinda Ardern reveals how Kiwis will be able to book their Covid vaccinations through a nationwide system ahead of mass rollout.

Anti-virus antibodies can persist in our bodies for up to one to two years after becoming infected with Covid-19 – something good bodes for booster shots in a post-pandemic world.

Antibodies play a vital role in fighting the immune system against pathogens like the coronavirus.

When a new virus is recognized, antibodies are specially created to bind to its “spike protein” and prevent it from entering our cells – while signaling other parts of the immune system to destroy the foreign invader.

A new study led by University of Canterbury mathematician, Associate Professor Alex James – and published online ahead of the peer review – modeled data from six articles to show that, in most patients, these antibodies last a long time.

The antibody response predicted by the model consisted of two stages: an initial peak after infection and a relatively rapid decline from this peak.

Then the antibody levels basically stabilized and the decline was much slower.

This stabilization of the antibodies suggested that the immune system was shifting from the original response to the virus to a longer-term memory response.

When the data sets were analyzed together, the model showed that the initial peak lasted about 17 days before the antibodies stabilized, and the “half-life” was 345 days.

This implied that, one to two years after infection, the antibodies would be at about 23% and 11% of their maximum level, respectively.

“This is a very encouraging result and if vaccine immunity follows a similar pattern, it gives hope that annual or even biennial booster vaccinations might be sufficient to provide long-lasting immunity,” said James and colleagues.

Study co-author and University of Auckland immunologist, Associate Professor Nikki Moreland, added: “This is very good news, because it means that most people are likely to develop immunological memory. after infection with Covid-19.

Covid

“This memory can then be activated and provide protection when a person is exposed to the virus again.”

So far, she said, data from Covid-19 vaccines indicated that the same antibody response pattern was likely to develop after vaccination, including a good long-term memory response.

“We still have to wait a few more months before this can be accurately modeled to determine if or when booster shots might be needed.”

One of the studies the modeling was based on included a group of 112 New Zealand patients previously infected with the virus, most of whom had mild symptoms.

This not only found their antibodies to last a long time, but they did so in a virus-free environment where Covid-19 had been cleared.

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Source: www.nzherald.co.nz
This notice was published: 2021-06-17 05:08:12

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